Face: The main development of the face occurs between the 4th and 8th weeks. Facial primordium Early in the 4th week, face is represented by an area around the mouth bounded cranially by the neural plate, caudally by the pericardial bulge and laterally by the mandibular precess of 1st pharyngeal arches. Facial development is induced by brain vesicles. Facial prominences In week 4 five facial prominences appear around stomodeum:-Single frontonasal prominence (FNP) above the stomodeum.-Paired maxillary prominences (Mx P) lateral to stomodeum.-Paired mandibular prominences (Md P) below stomodeum. The paired prominences are derivatives of the first pair of pharyngeal arches