This project illustrates the designing and implementation of a web based Pharmacy Sales and Inventory system for the. The primary aim of is to improve accuracy and enhance safety and efficiency in the pharmaceutical store by minimizing issues occur in day to day operations. Currently they are using a manual system which is very hard in handling. Managing the stock with paper records based on the expiry dates and the quantity available in the stock are some major problems identified in the problem domain. The system intends to minimize the workload of the staff and increase the value of the business to gain the competitive advantages in the pharmaceutical industry. The system allows different tasks for different users. They are administrator who can logging the system as different user roles to perform their functions separately. Administrator has all privileges of the system. Create users, generate reports for managerial decisions, manage employee attendance are some administrator tasks. In addition, the system will show a notification about expiry dates of drugs and stock ending details. It is easy to handle stock management through the software rather than working with paper records. Customers are the main asset of the business. So, the system will help to reduce waiting time of the customers. They can check the availability of the items before they come to the pharmacy by using the search facility provided in the pharmacy web site.