Sickle cell Crisis

Institution Kenya Medical Training College
Course DIPLOMA IN NURSING
Year 1st Year
Semester Unknown
Posted By stephen oyake rabilo
File Type pdf
Pages 47 Pages
File Size 833.89 KB
Views 1955
Downloads 0
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Description

Sickle cell disease (SCD) • A group of hereditary disorders in which the normal adult hemoglobin (hemoglobin A) is partly or completely replaced by abnormal sickle hemoglobin (HgbS). • The most common genetic hematologic condition in children • Transmitted by autosomal recessive pattern of inheritance. • Patient with this condition is homozygous for the sickle cell gene, i.e. both genes are abnormal. • The basic defect responsible for the sickling of erythrocytes is contained in the globin fraction of hemoglobin • The mode of transmission is hereditary • The gene that determines the production of HgbS is situated on an autosome.
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Institution: Kenya Medical Training College Year: 2018/2019 Semester: 1st Year, 1st Semester (1.1)