ANTI-MALARIAL DRUGS

Institution University
Course BACHELOR OF SCIENCE...
Year 1st Year
Semester Unknown
Posted By stephen oyake rabilo
File Type pdf
Pages 34 Pages
File Size 561.95 KB
Views 3495
Downloads 0
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Description

Malaria is transmitted by the bite of infected female anopheles mosquitoes. During feeding, mosquitoes inject sporozoites, which circulate to the liver, and rapidly infect hepatocytes, causing asymptomatic liver infection (hepatic phase)(absent in falciparum; malariae) . Merozoites released from the liver, rapidly infect erythrocytes to begin the asexual erythrocytic stage of infection that is responsible for human disease. Multiple rounds of erythrocytic development, with production of merozoites that invade additional erythrocytes, lead to large numbers of circulating parasites and clinical illness
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