General introduction: Public health and hygiene, human reproductive system, sex and sexuality. History of sexually transmitted diseases (STDs); History of Human Immunodeciency virus/ Acquired Immune deficiency Syndrome(HIV/AIDS), Comparative information on trends, global and local distribution, Justification of importance of course. Biology of HIV/AIDS; Overview of immune system, natural immunity to HIV/AIDS. The AIDS virus and its life cycle, disease progression, transmission and diagnosis. Discordant couples. Treatment and Management; nutrition, prevention and control; Abstain, Be faithful, Condom use, Destigmatize HIV/AIDS (ABCD) methods and an-tiretroviral drugs and vaccines. Pregnancy and AIDS. Management of HIV/AIDS patients. Social and cultural practices: Religion and AIDS. Social stigma on HIV/AIDS. Behavioral change. Voluntary Counseling and Testing Services. Gender and HIV/AIDS. Drug and alcohol abuse and HIV/AIDS. Poverty and AIDS. Families and AIDS orphans. Government policies: Global policies of AIDS. Legal rights of AIDS patients. AIDS Impact: Family /society setup, population, agriculture, education, health, industry, development, economy and other sectors.