SZL 3203 :CHEMICAL AND STRUCTURAL ORGANISATION OF THE MAMMALIAN BODY

Institution UNIVERSITY
Course BACHELOR OF BIOLOGI...
Year 1st Year
Semester Unknown
Posted By stephen oyake rabilo
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Description

The mammalian body is made of essentially non-living matter that is constituted and organized into forms that can contain and maintain life. The matter is in form of chemical compounds known as the chemicals of life. A description of these chemicals constitutes what is known as the chemical basis of life. There are two classes of chemical compounds in the mammalian body namely: a) Organic compounds. These are compounds that contain the element carbon covalently bound to other elements especially hydrogen, oxygen and nitrogen. b) Inorganic compounds. These are various types of salts/electrolytes in the body. Organic compounds There are four main classes of organic compounds in the body and these are referred to as macromolecules or biomolecules. They are: Carbohydrates. These are energy rich compounds that are readily broken down to release energy that runs the body’s life processes. They are also known as the biological fuel molecules. Carbohydrates are made of the elements carbon, hydrogen and oxygen and are simply abbreviated as CHO. Carbohydrates are synthesized by plants through the process of photosynthesis. Animals acquire carbohydrates by feeding on plants. There are two subdivisions of carbohydrates in the body depending on complexity as explained below: a) Sugars Sugars are small carbohydrate molecules found in the diets and in the bodies of animals. Sugars are also known as saccharides. Some saccharides consist of a single sugar molecule and are known as monosaccharides. The most common and well known monosaccharide in the mammalian body is glucose. A few saccharides consist of two sugar units joined together and are known as disaccharides or double sugars. Examples of disaccharides in mammalian diets are sucrose (cane sugar), lactose (milk sugar) and maltose (a breakdown product of starch). b) Polysaccharides -These are large carbohydrate molecules consisting of large numbers of sugar molecules joined together. Examples of polysaccharides in animal diets are starch, glycogen and cellulose.
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Reactions of Alkyl halides
In this type of reaction, a nucleophile reacts with haloalkane (the substrate) having a partial positive charge on the carbon atom bonded to halogen. A substitution reaction takes place and halogen atom, called leaving group departs as halide ion. Since the substitution reaction is initiated by a nucleophile, it is called nucleophilic substitution reaction
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Substitution and Elimination Electron Flow Pathway
Path Limitations There are three requirements for the S N 2 reaction. In order to be pushed out, the leaving group must be at least fair, usually good. The nucleophile also must be reactive enough to push out the leaving group. Finally, the back side of the tetrahedral carbon attacked must be accessible to the nucleophile and not blocked by other groups.
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The SN2 reaction
The hydroxide ion is a good nucleophile since the oxygen atom has a negative charge and a pair of unshared electrons. The carbon atom is electrophilic since it is bound to a (more electronegative) halogen, which pulls electron density away from the carbon, thus polarizing the bond with carbon bearing partial positive charge and the halogen bearing partial negative charge. The nucleophile is attracted to the electrophile by electrostatic charges. The nucleophile attacks the electrophilic carbon through donation of 2 electrons. Carbon can only have a maximum of 8 valence electrons, so as the carbon nucleophile bond is forming, then the carbon-leaving group bond must be breaking. Iodide is the leaving group since it leaves with the pair of electrons that once bound it to carbon.
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